Welcome to the Seegar Lab

We Study Ectodomain Shedding by Membrane-Tethered Proteases

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Welcome to the laboratory of Dr. Tom Seegar.  We are broadly interested in understanding how cells communicate and interpret the extracellular environment in normal and pathological conditions. In particular, we aim to investigate the universal concepts that underpin the function of membrane tethered proteases, such as the molecular basis for substrate selectivity, association with accessory proteins and regulation.

The University of Cincinnati

The laboratory is located in the University of Cincinnati, College of Medicine CARE Building and is a part of the Department of Molecular Genetics, Biochemistry, and Microbiology.

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